Article

The early postnatal activation of A2ARs protects BTBR mice against autism related behavior

2022-08-05

Abstract excerpt

<h4>Background: </h4> Studies mainly focused on the immediate effect of drugs on Autism spectrum disorders (ASD), the complex heterogeneous neurodevelopmental disorders, which been proved involved with the chronic inflammation of the central nervous system. Our studies have explored the positive role of activation of adenosine 2A receptors (A2ARs) in protect adult BTBR mice against autism related behavior from the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 55299a49-cd13-5b9a-aafd-27af091fc267
DOI: 10.21203/rs.3.rs-1918994/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The early postnatal activation of A2ARs protects BTBR mice against autism related behaviorDOI 10.21203/rs.3.rs-1918994/v1Read

Early postnatal activation of A2ARs alleviates social deficits by attenuating the abnormal infiltration of peripheral neutrophils in the BTBR T + Itpr3 tf /J mouse model of autismSemantic proximity Read

Neuroinflammation and Oxidative Stress in the Pathogenesis of Autism Spectrum DisorderSemantic proximity Read

Autism Spectrum Disorders: A Recent Update on Targeting Inflammatory Pathways with Natural Anti-Inflammatory AgentsSemantic proximity Read

Biomarkers for Early Diagnosis of Autism Obtained Through Bioinformatics Analysis of Human Blood SamplesSemantic proximity Read

Altered meningeal immunity contributing to the autism-like behavior of BTBR <i>T</i> <sup>+</sup> <i> Itpr3 <sup>tf</sup> </i> /J miceSemantic proximity Read

The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.Semantic proximity Read

Inflammatory profiles in the BTBR mouse: how relevant are they to autism spectrum disorders?Semantic proximity Read

Abnormal glutamate release in aged BTBR mouse model of autism.Semantic proximity Read

Identification of Important Genes of childhood autism and Construction of the Diagnostic ModelSemantic proximity Read

Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autismSemantic proximity Read

5-aminoisoquinolinone attenuates social behavior deficits and immune abnormalities in the BTBR T+ Itpr3tf/J mouse model for autism.Semantic proximity Read

Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior.Semantic proximity Read