Article
The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.
Behavioural brain research - 15 Aug 2013
Meyza Ksenia Z, Defensor Erwin B, Jensen Ashley L, Corley Michael J, Pearson Brandon L, Pobbe Roger L H, Bolivar Valerie J, Blanchard D Caroline, Blanchard Robert J
Abstract excerpt
Autism spectrum disorders (ASD) form a common group of neurodevelopmental disorders appearing to be under polygenic control, but also strongly influenced by multiple environmental factors. The brain mechanisms responsible for ASD are not understood and animal models paralleling related emotional and cognitive impairments may prove helpful in unraveling them. BTBR T+ tf/J (BTBR) mice display behaviors consistent...
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