Role of NFκB in age-related vascular endothelial dysfunction in humans

Abstract excerpt

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the United States and other industrialized societies.Older age is the major risk factor for development of CVD [1].Emerging evidence over the past 20 years suggests that the arterial vascular endothelium plays a critical role in the development of CVD, most notably, atherosclerosis.A healthy vascular endothelium is characterized by...

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