Article

Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in <i>GCKR</i> promote ectopic fat deposition

2019-01-21

Abstract excerpt

Dyslipidemia is a well-established risk factor for cardiovascular diseases. Although, advances in genome-wide technologies have enabled the discovery of hundreds of genes associated with blood lipid phenotypes, most of the heritability remains unexplained. Here we performed targeted resequencing of 13 bona fide candidate genes of dyslipidemia to identify the underlying biological functions. We sequenced 940 Sikh s...

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Literature Corpus work: 54e84aca-6123-547a-bd73-36d48ee6394b
DOI: 10.1101/526350

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