Article

Mechanistic contribution of CaV3.2 calcium channels to trigeminal neuralgia pathophysiology not clarified

2022-07-27

Abstract excerpt

Trigeminal neuralgia (TN) is a rare, yet debilitating trigeminal pain disorder, with jolts of supramaximal-debilitating pain in one or more of the three trigeminal branches. Familial TN is now recognized, with a recent report describing several human genetic polymorphisms. One affected gene is the voltage-gated calcium channel, CaV3.2 ( CACNA1H ), with 19 polymorphisms first described. A recent study in PAIN by G...

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Literature Corpus work: 54ba6b01-89f0-58ba-bca0-3198fe95de4b
DOI: 10.12688/f1000research.122997.2

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