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Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challenges

2 Jan 2019

Abstract excerpt

The human cytomegalovirus (HCMV) genome was sequenced by hierarchical shotgun almost 30 years ago. Over these years, low and high passaged strains have been sequenced, improving, albeit still far from complete, the understanding of the coding potential, expression dynamics and diversity of wild-type HCMV strains. Next-generation sequencing (NGS) platforms have enabled a huge advancement, facilitating the...

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PMID: 30604286
DOI: 10.1007/s11262-018-1627-3

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