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Genomic and Functional Characteristics of Human Cytomegalovirus Revealed by Next-Generation Sequencing

5 Mar 2014

Abstract excerpt

The complete genome of human cytomegalovirus (HCMV) was elucidated almost 25 years ago using a traditional cloning and Sanger sequencing approach. Analysis of the genetic content of additional laboratory and clinical isolates has lead to a better, albeit still incomplete, definition of the coding potential and diversity of wild-type HCMV strains. The introduction of a new generation of massively parallel...

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PMID: 24603756
DOI: 10.3390/v6031049

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