Article
Characterization of Human Cytomegalovirus Genome Diversity in Immunocompromised Hosts by Whole-Genome Sequencing Directly From Clinical Specimens.
The Journal of infectious diseases - 1 Jun 2017
Hage Elias, Wilkie Gavin S, Linnenweber-Held Silvia, Dhingra Akshay, Suárez Nicolás M, Schmidt Julius J, Kay-Fedorov Penelope C, Mischak-Weissinger Eva, Heim Albert, Schwarz Anke, Schulz Thomas F, Davison Andrew J, Ganzenmueller Tina
Abstract excerpt
Background: Advances in next-generation sequencing (NGS) technologies allow comprehensive studies of genetic diversity over the entire genome of human cytomegalovirus (HCMV), a significant pathogen for immunocompromised individuals. Methods: Next-generation sequencing was performed on target enriched sequence libraries prepared directly from a variety of clinical specimens (blood, urine, breast milk, respiratory...
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