Article

Understanding and Predicting Polycystic Ovary Syndrome through Shared Genetics with Testosterone, SHBG, and Chronic Inflammation

2023-10-18

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a common hormonal disorder that affects one out of eight women and has high metabolic and psychological comorbidities. PCOS is thought to be associated with increased systemic low-grade inflammation, but the underlying mechanisms remain unclear. Here we study the genetic relationship between PCOS and obesity, testosterone, sex hormone binding globulin (SHBG), and chronic inflamm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 54ad2821-7e5a-5829-b4d3-7badc381b72e
DOI: 10.1101/2023.10.17.23297115

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Understanding and Predicting Polycystic Ovary Syndrome through Shared Genetics with Testosterone, SHBG, and Chronic InflammationDOI 10.1101/2023.10.17.23297115Read

Polycystic Ovary Syndrome Physiologic Pathways Implicated Through Clustering of Genetic Loci.Semantic proximity Read

Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis CriteriaSemantic proximity Read

Genetics of the polycystic ovary syndrome.Semantic proximity Read

Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome.Semantic proximity Read

sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome.Semantic proximity Read

Sex Modifies the Effect of Genetic Risk Scores for Polycystic Ovary Syndrome on Metabolic PhenotypesSemantic proximity Read

sc-eQTL unveil Immunogenetic Architecture of Polycystic Ovary SyndromeSemantic proximity Read

Genetics of Polycystic Ovary Syndrome: What is New?Semantic proximity Read

Polycystic Ovary Syndrome Susceptibility Loci Inform Disease Etiological HeterogeneitySemantic proximity Read

Understanding polycystic ovary syndrome in light of associated key genesSemantic proximity Read

Molecular genetics of polycystic ovary syndrome: an update.Semantic proximity Read

Data-Driven Endocrine–Metabolic Phenotypes in Young Women With Polycystic Ovary Syndrome and Associations With Cardiometabolic Risk MarkersSemantic proximity Read