Back to search

Article

sc-eQTL unveil Immunogenetic Architecture of Polycystic Ovary Syndrome

2025-10-21

Abstract excerpt

<title>Abstract</title> <p> Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by metabolic, inflammatory, and reproductive dysfunction. We integrated genome-wide association study (GWAS) data, and single-cell expression quantitative trait loci (sc-eQTL) across various immune cells to elucidate the genetic and immune mechanisms underlying PCOS at the cellular level. Finally, we identi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cf2cbb50-a47f-54de-8371-050e7d802969
DOI
10.21203/rs.3.rs-6942288/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
sc-eQTL unveil Immunogenetic Architecture of Polycystic Ovary SyndromeDOI 10.21203/rs.3.rs-6942288/v1
sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome.Semantic proximity
Causal Genes and Immune-Epigenetic Mechanisms Underlying Polycystic Ovary Syndrome: A Multi-Omics Mendelian Randomization StudySemantic proximity
Evidence-based genetic variants to gene mapping and prioritization uncovers distinct molecular pathophysiology and therapeutic landscape in polycystic ovary syndrome patients of different ethnicities.Semantic proximity
Identification of immune cell infiltration and effective biomarkers of polycystic ovary syndrome by bioinformatics analysisSemantic proximity
A Systems-Level Transcriptomic Analysis of Polycystic Ovary Syndrome as a Mitochondrial-Immunometabolic DisorderSemantic proximity
Unravelling the molecular landscape of polycystic ovary syndrome (PCOS) and role of inflammation through transcriptomics analysis of human ovarian granulosa cellsSemantic proximity
Transcriptomic Profiling Reveals Potential Genes Involved in the Immune Landscape of Polycystic Ovary Syndrome: An Exploratory StudySemantic proximity
Identification of Immune-Associated Genes in Diagnosing Polycystic Ovary Syndrome with Metabolic Syndrome by Weighted Gene Co-expression Network AnalysisSemantic proximity
Deconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOSSemantic proximity
Integrative multi-omics analysis of druggable genes for therapeutic target identification in polycystic ovary syndrome.Semantic proximity
Immunophenotypic Profiles in Polycystic Ovary SyndromeSemantic proximity
Transcriptome Profiling Revealed the Relationship Between Immune-Related Genes and m6A Modifiers in Polycystic Ovary SyndromeSemantic proximity
Select a neighboring publication to make it the new centre.