Article

Myelodysplastic Disease Associated with Deletions of Chromosome 5q Region

2025-10-14

Abstract excerpt

The only cytogenetic alteration defining a subtype of a myelodysplastic syndrome is represented by the deletion of the long arm of chromosome 5 (del(5q)), now classified as MDS with isolated del(5q). This subtype is associated with a peculiar phenotype mainly dependent by the haploinsufficiency of several genes located on the deleted arm of chromosome 5. These patients show a good prognosis and respond to treatmen...

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Literature Corpus work: 54a5ec5c-1418-582d-9c02-1459585f167e
DOI: 10.20944/preprints202510.0993.v1

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