The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities

Abstract excerpt

BACKGROUND: To define the prognosis in myelodysplastic syndrome (MDS) and deletion 5q with or without other cytogenetic abnormalities. METHODS: Patients with MDS (<20% blasts) and evaluable cytogenetic studies (1966-present) were reviewed. Outcome of patients with deletion 5q or with loss of chromosome 5 (monosomy 5) was analyzed. RESULTS: Of 2743 patients analyzed, 287 (10%) had deletion 5q and 216 (8%) had...

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