Article
Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: clinicopathologic correlations and new insights from the pre-lenalidomide era.
American journal of hematology - 1 Sept 2008
Holtan Shernan G, Santana-Davila Rafael, Dewald Gordon W, Khetterling Rhett P, Knudson Ryan A, Hoyer James D, Chen Dong, Hanson Curtis A, Porrata Luis, Tefferi Ayalew, Steensma David P
Abstract excerpt
To better estimate prognosis for patients with myelodysplastic syndromes (MDS) associated with clonal interstitial deletions of the long arm of chromosome 5 (del(5q)), we reviewed the medical records of 130 adults with del(5q) MDS seen at our institution over a 15-year period. Overall median survival of this cohort was 9.5 months, shorter than reported in earlier series. The least favorable outcomes are...
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