Article

Prioritized RNA modification enzymes as risk genes for bipolar I disorder and schizophrenia

2026-07-31

Abstract excerpt

<title>Abstract</title> <p> Enzyme-mediated RNA modifications provide a versatile and dynamic regulatory layer in brain development and neural function, orchestrated by over 100 RNA modification proteins (RMPs). A systematic assessment of contribution by common genetic variants in RMP genes to psychiatric disorders has been lacking. Here we curated 123 human RMPs—corresponding to 31 modification types on 6 RNA b...

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Literature Corpus work: 546c7849-607c-5edb-9ffa-338841bc9942
DOI: 10.21203/rs.3.rs-10393507/v1

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