Article

The GRACE Cycle: A General Large-Language-Model Framework for Phenotype Discovery with Unknown Cluster Number

2026-07-14

Abstract excerpt

<title>Abstract</title> <p>Phenotype discovery—the data-driven identification of clinically or biologically meaningful subgroups—is fundamental to precision medicine, but conventional clustering methods require the number of clusters K to be specified a priori and struggle with heterogeneous, multimodal, or longitudinal data. We introduce the GRACE Cycle (Generate hypothesis, Retrieve evidence, Align, Converge, E...

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Literature Corpus work: 54636f3d-a8c3-5880-8f43-289a1fced7b8
DOI: 10.21203/rs.3.rs-10048424/v1

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