Article

Exploratory dried blood spot metabolomics identifies pathway-level convergence with ME/CFS biology in a self-reported PEM-like fatigue phenotype

2026-06-10

Abstract excerpt

<h4>Background</h4> Plasma and serum metabolomic studies of myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) have repeatedly implicated hypometabolic, lipid, mitochondrial, redox and tryptophan-kynurenine pathways, but prior cohorts have been modest in size and have used heterogeneous case definitions. Whether similar pathway-level signals are detectable at scale in dried blood spots (DBS), across qu...

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Literature Corpus work: f1b53feb-4080-569c-bddd-436cca368594
DOI: 10.64898/2026.06.08.26355197

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Exploratory dried blood spot metabolomics identifies pathway-level convergence with ME/CFS biology in a self-reported PEM-like fatigue phenotypeDOI 10.64898/2026.06.08.26355197Read

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