Back to search

Article

Combination of immunotherapy and anti-EGFR agents in immunotherapy refractory head neck cancer recurrent and metastatic head neck squamous cell carcinoma

2026-04-29

Abstract excerpt

<title>Abstract</title> <p>Background Immunotherapy has become a standard treatment for recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC); however, response rates remain modest, and long-term survival is limited. Preclinical studies suggest that inhibiting the epidermal growth factor receptor (EGFR) pathway may enhance antigen presentation and augment the efficacy of immune checkpoint...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
83173230-6c0e-598f-ba13-f9916e83a930
DOI
10.21203/rs.3.rs-9000074/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Combination of immunotherapy and anti-EGFR agents in immunotherapy refractory head neck cancer recurrent and metastatic head neck squamous cell carcinomaDOI 10.21203/rs.3.rs-9000074/v1
Immunotherapy with PD-1 Inhibitor Nivolumab in Recurrent/Metastatic Platinum Refractory Head and Neck Cancers: The Early Experience of Two Academic CenterSemantic proximity
Clinical characteristics and prognostic analysis of 95 cases of recurrent/metastatic nasopharyngeal carcinoma treated with immunotherapy: a single-center retrospective studySemantic proximity
Application of molecular targeted therapies in the treatment of head and neck squamous cell carcinoma (Review)Semantic proximity
Combination of Immunotherapy and Radiotherapy for Recurrent Malignant Gliomas: Results From a Prospective Study.Semantic proximity
Predictive and prognostic factors for immunotherapy response in head and neck squamous cell carcinoma: a narrative review.Semantic proximity
Multicenter validation of an assay to predict anti-PD-1 disease control in patients with recurrent or metastatic Head and Neck Squamous Cell Carcinoma: The PREDAPT StudySemantic proximity
Multicenter Phase II Study of Panitumumab in Platinum Pretreated, Advanced Head and Neck Squamous Cell Cancer.Semantic proximity
Comparative Analysis of Clinical Outcomes Between Neoadjuvant Chemoimmunotherapy and Neoadjuvant Chemoradiotherapy in Patients with Resectable Locally Advanced Esophageal Squamous Cell Carcinoma: A Multicenter, Retrospective StudySemantic proximity
Immunotherapy for TKI-resistant, EGFR L858R-mutated non-small cell lung cancer: a systematic review and meta-analysis of randomized and single-arm studies.Semantic proximity
Relative efficacies of EGFR-TKIs and immune checkpoint inhibitors for treatment of recurrent non-small cell lung cancer after surgerySemantic proximity
A phase II study of temsirolimus and erlotinib in patients with recurrent and/or metastatic, platinum-refractory head and neck squamous cell carcinoma.Semantic proximity
The 'Triple Threat': Extracapsular Extension, Perineural Invasion, and Lymphovascular Invasion as Predictors of Adjuvant Chemoradiation Failure in Head and Neck Squamous Cell CarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.