Article

Complement-dependent mpox virus-neutralizing antibodies in infected and vaccinated individuals

2023-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Mpox virus (MPXV) caused a multi-country outbreak in non-endemic areas in 2022. The Modified Vaccinia Ankara (MVA)-based vaccine was used as prophylaxis, but its effectiveness remains poorly characterized. Here, we developed two assays for quantification of neutralizing antibodies (NAbs), using MVA-GFP or a recently isolated MPXV. We measured NAb levels in 470 sera from control, MPXV-infected or...

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Identifiers and source

Literature Corpus work: 54255b6a-07d3-5c1d-951f-04aec1067165
DOI: 10.1101/2023.04.14.23288385

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