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Metformin combats high glucose-induced  damage  to the osteogenic differentiation of human periodontal ligament  stem  cells via inhibition of MAPK pathway mediated through NPR3

2022-01-18

Abstract excerpt

<title>Abstract</title> <p>Background High glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells (PDLSCs) has long been a challenge to periodontal regeneration for diabetic individuals. Metformin is an anti-hyperglycemic drug that exhibiting abundant biological activities associated with cell metabolism and downstream tissue regeneration. However, how metformin combats...

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Literature Corpus work
1b5acf38-365d-5b4f-8e58-30852156c9f6
DOI
10.21203/rs.3.rs-1217102/v1
Open publication

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Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of MAPK pathway mediated through NPR3DOI 10.21203/rs.3.rs-1217102/v1
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