Article

Sodium Butyrate Inhibits Osteogenesis In Human Periodontal Ligament Stem Cells By Suppressing Smad1 Expression: A Randomized Controlled Trial

2022-03-03

Abstract excerpt

<h4>Background: </h4> Butyrate is a major subgingival microbial metabolite that is closely related to periodontal disease. It affects the proliferation and differentiation of mesenchymal stem cells. However, the mechanisms by which butyrate affects the osteogenic differentiation of periodontal ligament stem cells (PDLSCs) remain unclear. Here, we investigated the effect of sodium butyrate (NaB) on the osteogenic d...

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Literature Corpus work: 9d8f00d9-553d-5308-b7b2-8a7f6490bb3a
DOI: 10.21203/rs.3.rs-1393541/v1

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