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Article

An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae.

The Journal of biological chemistry - 10 Apr 2009

Lee Jeongmi, Sperandio Vanessa, Frantz Doug E, Longgood Jamie, Camilli Andrew, Phillips Margaret A, Michael Anthony J

Abstract excerpt

Polyamines are small organic cations found in all cells, and the biosynthetic pathway is well described in eukaryotes and Escherichia coli. The characterized pathway uses decarboxylated S-adenosylmethionine as the aminopropyl group donor to form spermidine from putrescine by the key enzymes S-adenosylmethionine decarboxylase and spermidine synthase. We report here the in vivo characterization of an alternative...

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Identifiers

PMID: 19196710
DOI: 10.1074/jbc.M900110200
PMCID: PMC2665113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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