Article

Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry

2024-03-31

Abstract excerpt

Collagen cross-links created by the lysyl oxidase and lysyl hydroxylase families of enzymes are a significant contributing factor to the biomechanical strength and rigidity of tissues, which in turn influence cell signaling and ultimately cell phenotype. In the clinic, the proteolytically liberated N-terminal cross-linked peptide of collagen I (NTX) is used as a biomarker of bone and connective tissue turnover, wh...

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Literature Corpus work: 53e6a7ae-bda5-5dac-8af5-d6e03fdf9dd1
DOI: 10.1101/2024.03.31.587441

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