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Decreased expression of the HDAC2 disrupts the SLIT-ROBO signaling pathway and induced angiogenesis in placental endothelial cells in preeclampsia

2024-03-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Preeclampsia is characterized by reduced histone deacetylase 2 (HDAC2) expression in placental tissue HDAC2 enrichment positively affects angiogenesis as it helps prevent endothelial cell dysfunction. Additionally, research has demonstrated that the SLIT2-ROBO signaling pathway influences preeclampsia. Bioinformatics analysis has suggested that HDAC2 may have a...

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Literature Corpus work
53b1322f-47be-5311-a595-983831c096ca
DOI
10.21203/rs.3.rs-4143819/v1
Open publication

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Decreased expression of the HDAC2 disrupts the SLIT-ROBO signaling pathway and induced angiogenesis in placental endothelial cells in preeclampsiaDOI 10.21203/rs.3.rs-4143819/v1
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