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Article

Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems

2018-01-17

Abstract excerpt

The theoretically unlimited spatial resolution of fluorescence nanoscopy often comes at the expense of time, contrast and increased dose of energy for recording. Here, we developed MoNaLISA, for Molecular Nanoscale Live Imaging with Sectioning Ability, a nanoscope capable of imaging structures at a scale of 45–65 nm within the entire cell volume at low light intensities (W–kW/cm 2 ). Our approach, based on revers...

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Literature Corpus work
53a41d4f-3c91-54aa-ba23-b537ed7a3259
DOI
10.1101/248880
Open publication

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Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systemsDOI 10.1101/248880
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