Back to search

Article

Not All Predictors Of RCC Clusters Are The Same: An individual sample predictive model to classify patients with metastatic renal cell carcinoma

2026-06-29

Abstract excerpt

Clear cell renal cell carcinoma (RCC) patients have multiple approved therapies, including anti-angiogenesis tyrosine kinase inhibitors (TKIs) and immuno-oncology therapies (IO), but lack a clinically validated biomarker. Using RNAseq data from the IMmotion 151 clinical trial (IM151) 1–3 , 7 RCC biologic clusters have been defined 3 . Several groups have attempted to predict these clusters on various RCC dataset...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
538f6b8e-5f3b-50ab-b942-5412a40f49ad
DOI
10.64898/2026.06.24.734285
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Not All Predictors Of RCC Clusters Are The Same: An individual sample predictive model to classify patients with metastatic renal cell carcinomaDOI 10.64898/2026.06.24.734285
Subgroup-Independent Mapping of Renal Cell Carcinoma—Machine Learning Reveals Prognostic Mitochondrial Gene Signature Beyond Histopathologic BoundariesSemantic proximity
Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer.Semantic proximity
A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapySemantic proximity
Identification of clear cell renal cell carcinoma subtypes by integrating radiomics and transcriptomicsSemantic proximity
Development of a Prognostic Index for Clear Cell Renal Cell Carcinoma Using Machine Learning and Multi-omics Analysis to Enhance Clinical Outcomes and Drug SensitivitySemantic proximity
Single‐cell analysis reveals metastatic cell heterogeneity in clear cell renal cell carcinomaSemantic proximity
A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profilesSemantic proximity
DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinomaSemantic proximity
Select a neighboring publication to make it the new centre.