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Development of a Prognostic Index for Clear Cell Renal Cell Carcinoma Using Machine Learning and Multi-omics Analysis to Enhance Clinical Outcomes and Drug Sensitivity

2026-08-03

Abstract excerpt

<title>Abstract</title> <p>Background Clear cell renal cell carcinoma (KIRC) represents the major malignant subtype of kidney cancer and shows pronounced biological heterogeneity. For patients with advanced disease, therapeutic resistance and the lack of stable prognostic markers continue to keep 5-year survival below 15%. Cancer driver genes (CDGs) participate in malignant transformation and tumor progression,...

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Literature Corpus work
9bbd1852-3484-5216-91ab-9974776dc381
DOI
10.21203/rs.3.rs-10277358/v1
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Development of a Prognostic Index for Clear Cell Renal Cell Carcinoma Using Machine Learning and Multi-omics Analysis to Enhance Clinical Outcomes and Drug SensitivityDOI 10.21203/rs.3.rs-10277358/v1
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