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Article

Collectives of diagnostic biomarkers identify high-risk subpopulations of hematuria patients: exploiting heterogeneity in large-scale biomarker data

17 Jan 2013

Abstract excerpt

BACKGROUND: Ineffective risk stratification can delay diagnosis of serious disease in patients with hematuria. We applied a systems biology approach to analyze clinical, demographic and biomarker measurements (n = 29) collected from 157 hematuric patients: 80 urothelial cancer (UC) and 77 controls with confounding pathologies. METHODS: On the basis of biomarkers, we conducted agglomerative hierarchical clustering...

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Share to Bladder and Urothelial Cancer Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23327460
DOI: 10.1186/1741-7015-11-12

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