Article

Subclones of Bone Marrow CD34+ Cells in Acute Myeloid Leukemia at Diagnosis Confer Responses of Patients to Induction Chemotherapy

2021-11-15

Abstract excerpt

<h4>Background: </h4> Acute myeloid leukemia (AML) is a fatal hematopoietic malignancy which has a prognosis that varies with genetic heterogeneity of its hematopoietic stem/progenitor cells(HSCPs). Intensive induction chemotherapy with cytarabine and anthracycline has been the standard of care for newly diagnosed AML, but about 30% of patients have no response to this regimen. The resistance mechanisms require de...

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Literature Corpus work: 534eabcc-666d-528c-b753-6d2d6496dbd6
DOI: 10.21203/rs.3.rs-1047797/v1

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Subclones of Bone Marrow CD34+ Cells in Acute Myeloid Leukemia at Diagnosis Confer Responses of Patients to Induction ChemotherapyDOI 10.21203/rs.3.rs-1047797/v1Read

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