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Genetics and Pathologic Landscape of Lineage Switch of Acute Leukemia during Therapy: A Multi-institutional Study

2023-10-16

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<title>Abstract</title> <p>The dismal outcome of acute leukemia undergoing immunophenotype-switch, compounded by the increased incidence in the era of immunotherapy, highlights the need for in-depth systemic studies. We investigated the clinicopathological, cytogenetic, and molecular features of 33 patients experiencing switch between acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). The median...

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Literature Corpus work: 52e18cbb-4275-5dc5-9131-f4526b7b5348
DOI: 10.21203/rs.3.rs-3422078/v1

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