Article
A Prognostic Model for Prostate Cancer Patients Based on Two DNA Damage Response Mutation-Related Immune Genes.
Cancer biotherapy & radiopharmaceuticals - 1 May 2024
Wang Jian, Jiang Li, Shang Zhenhua, Ye Zhaohua, Yuan Dan, Cui Xin
Abstract excerpt
Background: DNA damage response (DDR) mutation-related genes and composition of immune cells are core factors affecting the effectiveness of immune checkpoint inhibitor therapy. The aim of this study is to combine DDR with immune-related genes to screen the prognostic signature for prostate cancer (PCa). Methods: Gene expression profile and somatic mutation were downloaded from The Cancer Genome Atlas (TCGA)....
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