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Comprehensive analysis of tumor mutation burden and immune microenvironment in prostate cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Oct 2022

Liao Junqun, Ye Yuan, Xu Xuren

Abstract excerpt

PURPOSE: Prostate adenocarcinoma (PRAD) is a high incidence of malignant tumor of the urinary system and the second most common male cancer in the world. Immune checkpoint inhibitor (ICIS) therapy is becoming a new hope for cancer treatment. METHODS: To realize the possibility of PRAD patients benefiting from ICIS treatment, we analyzed the mutation spectrum of all PRAD patients, calculated the TMB of each PRAD...

Topics

Biomarkers, Tumor
Humans
Immunotherapy
Male
Mutation
Prognosis
Prostatic Neoplasms
Tumor Microenvironment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35732871
DOI: 10.1007/s12094-022-02857-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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