Article

Sampling Conformational Ensembles of Highly Dynamic Proteins via Generative Deep Learning

2024-06-28

Abstract excerpt

<title>Abstract</title> <p>Proteins are inherently dynamic, and their conformational ensembles are functionally important in biology. Large-scale motions may govern protein structure–function relationship, and numerous transient but stable conformations of intrinsically disordered proteins (IDPs) can play a crucial role in biological function. Investigating conformational ensembles to understand regulations and d...

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Literature Corpus work: 524273e2-bba8-53d4-857a-3ab20ff7e051
DOI: 10.21203/rs.3.rs-4301803/v1

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