Article

KMT2C is implicated in hypothalamic hamartoma resulting in central precocious puberty

2022-07-14

Abstract excerpt

Precocious puberty (PP) is defined as the onset of puberty in early childhood, which presents with testicular enlargement before 9 years in boys, and breast budding and the onset of menstruation before 8 years in girls. Hypothalamic hamartoma (HH) is among the most common cause of central PP (CPP). As the pathogenesis of HH has not been elucidated to date, we explored the underlying molecular changes in three HH c...

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Literature Corpus work: 5231ac72-f9d5-5946-be20-bc80348a4ee2
DOI: 10.21203/rs.3.rs-1717887/v1

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