DLK1, Notch Signaling and the Timing of Puberty

Abstract excerpt

Abstract The factors that trigger human puberty are among the central mysteries of reproductive biology. Several approaches, including mutational analysis of candidate genes, large-scale genome-wide association studies, whole exome sequencing, and whole genome sequencing have been performed in attempts to identify novel genetic factors that modulate the human hypothalamic–pituitary–gonadal axis to result in...

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• Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
• Share to Hypothalamic control of reproductive hormones
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