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Article

The genetic etiology is a relevant cause of central precocious puberty.

European journal of endocrinology - 5 Jun 2024

Canton Ana Pinheiro Machado, Seraphim Carlos Eduardo, Montenegro Luciana Ribeiro, Krepischi Ana Cristina Victorino, Mendonca Berenice Bilharinho, Latronico Ana Claudia, Brito Vinicius Nahime

Abstract excerpt

OBJECTIVES: The etiology of central precocious puberty (CPP) has expanded with identification of new genetic causes, including the monogenic deficiency of Makorin-Ring-Finger-Protein-3 (MKRN3). We aimed to assess the prevalence of CPP causes and the predictors of genetic involvement in this phenotype. DESIGN: A retrospective cohort study for an etiological survey of patients with CPP from a single academic...

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PMID: 38857188
DOI: 10.1093/ejendo/lvae063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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