Article

Expression of immune checkpoint VISTA represents a differentiated state of cancer cells and plays a role in regulating actin cytoskeleton

2026-08-26

Abstract excerpt

Immune checkpoint blockade has revolutionized cancer therapy, but the therapeutic efficacy is limited. Clinical trials on blockade of newly identified immune checkpoints didn't show promising result, suggesting that it might be insufficient to understand the function of immune checkpoints in cancer merely in the context of immunity. Here, we found mutually exclusive expression patterns of the immune checkpoint VIS...

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Literature Corpus work: 52096609-1ec3-537a-bd46-56fad1c4e7ea
DOI: 10.64898/2026.08.24.746888

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