Back to search

Article

Epigenetic signature of heterogeneity in aging: Findings from the Canadian Longitudinal Study on Aging

2025-08-27

Abstract excerpt

Human aging does not follow a single trajectory. Epigenetic changes offer insight into the heterogeneity in aging by reflecting the combined influence of genetic, environmental, and lifestyle factors on the timing and progression of age-related changes beyond what chronological age alone can explain. Emerging research in cancer and aging highlights the importance of methylation variability as a marker of biologica...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
51bfa002-0e28-5ed4-9d0f-f3b26eef2a4b
DOI
10.1101/2025.08.25.671156
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Epigenetic signature of heterogeneity in aging: Findings from the Canadian Longitudinal Study on AgingDOI 10.1101/2025.08.25.671156
The Aging Epigenome: Integrative Analyses Reveal Functional Overlap with Alzheimer’s DiseaseSemantic proximity
Dynamic methylome modification is associated with mutational signatures in aging and the etiology of diseaseSemantic proximity
Epigenome‐wide analysis of frailty: Results from two European twin cohortsSemantic proximity
From aging to Alzheimer’s disease: concordant brain DNA methylation changes in late lifeSemantic proximity
Genome-wide multi-layered epigenomic profiling across human agingSemantic proximity
Heterogeneity of Human Aging and Its AssessmentSemantic proximity
Dynamic DNA Methylation During Aging: A “Prophet” of Age-Related OutcomesSemantic proximity
An epigenetic biomarker of aging for lifespan and healthspanSemantic proximity
Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twinsSemantic proximity
An epigenetic biomarker of aging for lifespan and healthspanSemantic proximity
The epigenetic landscape of age-related diseases: the geroscience perspective.Semantic proximity
A decade of epigenetic change in aging twins: genetic and environmental contributions to longitudinal DNA methylationSemantic proximity
Select a neighboring publication to make it the new centre.