Article
Yiqi Yangxue Qufeng Mixture alleviates knee osteoarthritis by modulating mitochondrialoxidative stress and suppressing ferroptosis via the PRKCA-MAPK/ERK axis
2026-08-10
Abstract excerpt
<title>Abstract</title> <p> <bold>Background</bold> Knee osteoarthritis (KOA) is one of the most common degenerative joint diseases globally, which significantly impairs patients' quality of life. Currently, effective approaches capable of reversing or significantly delaying disease progression are still lacking, and the long-term prognosis for patients remains suboptimal. This experiment aimed to validate the...
Topics
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- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
- Inflammatory mediators and NSAID effects
- Natural product bioactivities and synthesis
- Osteoarthritis Treatment and Mechanisms
- Pharmacological Effects of Natural Compounds
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 51860266-e725-5220-a96c-242b72bde6a3
- DOI
- 10.21203/rs.3.rs-10091914/v1
