Article

Machine learning-based identification of ferroptosis-related biomarkers in osteoarthritis

2023-09-01

Abstract excerpt

<h4>Background: </h4> Osteoarthritis (OA) is the most common joint disease and a major cause of chronic disability in elderly individuals. OA is characterized by degeneration of articular cartilage, structural changes in the subchondral bone structure, and formation of bony encumbrances, with the main clinical manifestations being joint swelling, pain, stiffness, deformity, and limited mobility. Ferroptosis is a n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7685fca-7f26-58fc-8376-cc343aae2e46
DOI: 10.21203/rs.3.rs-3304065/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Machine learning-based identification of ferroptosis-related biomarkers in osteoarthritisDOI 10.21203/rs.3.rs-3304065/v1Read

Machine learning identifies ferroptosis-related genes as potential diagnostic biomarkers for osteoarthritisSemantic proximity Read

Screening of diagnostic biomarkers for Ferroptosis-related osteoarthritis and construction of a risk-prognosis modelSemantic proximity Read

Ferroptosis-related genes LPCAT3 and PGD are potential diagnostic biomarkers for osteoarthritisSemantic proximity Read

Identifying characteristic genes of ferroptosis in osteoarthritis based on machine learning and analysis of immune infiltrationSemantic proximity Read

Characterization and role exploration of ferroptosis-related genes in osteoarthritisSemantic proximity Read

Identification and verification of novel ferroptosis genes in osteoarthritis synovial tissue through bioinformatics analysisSemantic proximity Read

Integrating multiple microarray datasets to explore the significance of ferroptosis regulators in the diagnosis and subtype classification of osteoarthritisSemantic proximity Read

Identification and verification of ferroptosis-related genes in the synovial tissue of osteoarthritis using bioinformatics analysisSemantic proximity Read

Ferroptosis in Osteoarthritis: Towards Novel Therapeutic StrategySemantic proximity Read

Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro studySemantic proximity Read

Ferroptosis-related genes and pathways in knee osteoarthritis cartilage degeneration: based on bioinformatics technology and vivo experimental verificationSemantic proximity Read

Decoding ferroptosis: transforming orthopedic disease managementSemantic proximity Read