Article
Network pharmacology, bioinformatics, molecular docking and experimental verification of the mechanism of HXZTS treatment on osteoarthritis synovium
2025-09-29
Abstract excerpt
<h4>Background</h4> Osteoarthritis (OA) is a prevalent joint disease characterized by synovial inflammation and synovial fibroblast dysfunction. Elucidating the molecular mechanisms underlying synovial tissue impairment in OA is crucial for developing targeted therapeutic interventions. Huoxuezhitongsan (HXZTS), a traditional Chinese medicine formula, has shown promising therapeutic effects in treating OA, but it...
Topics
Open a Topic to create a Post that cites this publication.
- Flavonoids in Medical Research
- Inflammatory mediators and NSAID effects
- Natural Compounds in Disease Treatment
- Natural product bioactivities and synthesis
- Osteoarthritis Treatment and Mechanisms
- Pharmacological Effects of Natural Compounds
- Phytochemical compounds biological activities
- Rheumatoid Arthritis Research and Therapies
Identifiers and source
- Literature Corpus work
- 2ab11871-979f-57e7-a023-e2f1274a2952
- DOI
- 10.1101/2025.09.25.678423
