Article

Bidirectional Mendelian randomization study shows causal relationship between high- altitude adaptation and liver diseases

2024-03-25

Abstract excerpt

To investigate the causality between high-altitude adaptation (HAA) and multiple liver diseases, we applied a Mendelian randomization (MR) study. The genome-wide association studies (GWASs) of HAA and eleven phenotypes of liver diseases/traits were used for this study, including autoimmune hepatitis (AIH), alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), hepatic bile du...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 517dcf3b-fd6a-5eba-9461-ff727be5b91e
DOI: 10.21203/rs.3.rs-4125106/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bidirectional Mendelian randomization study shows causal relationship between high- altitude adaptation and liver diseasesDOI 10.21203/rs.3.rs-4125106/v1Read

Using Mendelian Randomization to Dissect the Relationship Between High-Altitude Adaptation and Liver Diseases/Traits.Semantic proximity Read

Liver function indicators and risk of hepatocellular carcinoma: a bidirectional mendelian randomization studySemantic proximity Read

Causal Relationships Between High-Altitude Adaptation, Metabolic Traits, and Tumors: Insights from Mendelian Randomization.Semantic proximity Read

Study on molecular mechanisms related to hepatic fibrosis by Mendelian randomization combined with transcriptome analysisSemantic proximity Read

Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study.Semantic proximity Read

Causal effects of plasma metabolites on autoimmune hepatitis (AIH): a bidirectional two-sample mendelian randomization study.Semantic proximity Read

Aminotransferases as causal factors for metabolic syndrome: A bidirectional Mendelian randomization study.Semantic proximity Read

Hematologic traits and primary biliary cholangitis: a Mendelian randomization study.Semantic proximity Read

Love-hate relationship between hepatitis B virus and type 2 diabetes: a Mendelian randomization studySemantic proximity Read

Association between autoimmune liver diseases and chronic hepatitis B: A multivariable Mendelian randomization study in European population.Semantic proximity Read

Systemic inflammatory regulators and risk of acute-on-chronic liver failure: A bidirectional mendelian-randomization studySemantic proximity Read

Height and risk of liver fibrosis progression: A multivariable Mendelian randomization studySemantic proximity Read