Article

Identification of potential colorectal-cancer-protective bioactive natural compounds in the human gut microbiome

2026-02-18

Abstract excerpt

Increasing evidence links the gut microbiome to the development and progression of colorectal cancer (CRC). Despite the remarkable diversity of microbial biosynthetic gene clusters (BGCs), no CRC-protective bioactive natural compounds originating from gut microbiome BGCs have yet been detected. Here, we investigated BGCs within de novo gut metagenome-assembled species reconstructed from 559 individuals, including...

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Literature Corpus work: 5173bb08-7e69-55f4-9b5f-3d09104f3744
DOI: 10.64898/2026.02.17.706414

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