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Dysbiosis of human gut microbiome in young-onset colorectal cancer

19 Nov 2021

Abstract excerpt

The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients. Through 16S rRNA gene sequencing, 728 samples are collected to identify microbial markers, and an independent cohort of 310 samples is used to validate the results. Furthermore, species-level and functional analysis are performed by...

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Colorectal Cancer Screening and Detection
Genetic factors in colorectal cancer
Gut microbiota and health

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34799562
DOI: 10.1038/s41467-021-27112-y

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