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Article

Immunoregulatory Role of the Mechanosensitive Ion Channel Piezo1 in Inflammation and Cancer

26 Dec 2022

Abstract excerpt

Piezo1 was originally identified as a mechanically activated, nonselective cation ion channel, with significant permeability to calcium ions, is evolutionally conserved, and is involved in the proliferation and development of various types of cells, in the context of various types of mechanical or innate stimuli. Recently, our study and work by others have reported that Piezo1 from all kinds of immune cells is...

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PMID: 36615408
DOI: 10.3390/molecules28010213

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