Article

In Vitro and In Vivo Evaluation of Human Adenovirus Type 49 as a Vector for Therapeutic Applications

2021-07-22

Abstract excerpt

The human adenovirus phylogenetic tree is split across seven species (A-G). Species D adenoviruses offer potential advantages for gene therapy applications, with low rates of preexisting immunity detected across screened populations. However, many aspects of the basic virology of species D, such as their cellular tropism, receptor usage and in vivo biodistribution profile, remain unknown. Here, we have characteriz...

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Literature Corpus work: 5147b8d6-a37e-54f1-bd06-ca9f44dbbb1e
DOI: 10.20944/preprints202107.0153.v2

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