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Perspective on Adenoviruses: Epidemiology, Pathogenicity, and Gene Therapy

19 Aug 2019

Abstract excerpt

Human adenoviruses are large (150 MDa) doubled-stranded DNA viruses that cause respiratory infections. These viruses are particularly pathogenic in healthy and immune-compromised individuals, and currently, no adenovirus vaccine is available for the general public. The purpose of this review is to describe (i) the epidemiology and pathogenicity of human adenoviruses, (ii) the biological role of adenovirus vectors...

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PMID: 31430920
DOI: 10.3390/biomedicines7030061

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