Article

Normative modelling of cortical networks identifies subtypes of type 2 diabetes associated with distinct clinical and transcriptomic profiles

2026-08-27

Abstract excerpt

Type 2 diabetes (T2D) is characterized by substantial clinical heterogeneity, yet its neurobiological substrates remain unclear. Here, we leverage normative modelling of cortical morphometric networks to quantify individual-level brain deviations using structural MRI data from 3,723 participants (1,941 T2D patients and 1,782 healthy controls) across three independent cohorts. Data-driven clustering reveals two rob...

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Literature Corpus work: 51401a3c-6a84-59d5-8c69-eed7cc2b8d6f
DOI: 10.64898/2026.08.23.746498

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