Article

Human miRNome Profiling in Colon Adenoma-carcinoma Sequence Reveal Early Deregulation of miR-1246, Which Exhibits Oncogenic Properties in Vitro by Targeting AXIN2 and CFTR

2021-06-02

Abstract excerpt

<h4>Background: </h4> Regulatory changes occurring early in colorectal cancer development remain poorly investigated. Since the majority of cases develop from polyps in the adenoma-carcinoma pathway, a search of early molecular features, such as aberrations in miRNA expression occurring prior to cancer development, would enable identification of potentially causal, rather than consequential, candidates in the prog...

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Literature Corpus work: 513d37bd-14c8-50c4-af69-3d7d658a068c
DOI: 10.21203/rs.3.rs-558860/v1

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Human miRNome Profiling in Colon Adenoma-carcinoma Sequence Reveal Early Deregulation of miR-1246, Which Exhibits Oncogenic Properties in Vitro by Targeting AXIN2 and CFTRDOI 10.21203/rs.3.rs-558860/v1Read

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