Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex patterns of altered MicroRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2011

Bartley Angela N, Yao Hui, Barkoh Bedia A, Ivan Cristina, Mishra Bal M, Rashid Asif, Calin George A, Luthra Rajyalakshmi, Hamilton Stanley R

Abstract excerpt

PURPOSE: MicroRNAs are short noncoding RNAs that regulate gene expression and are over- or underexpressed in most tumors, including colorectal adenocarcinoma. MicroRNAs are potential biomarkers and therapeutic targets and agents, but limited information on microRNAome alterations during progression in the well-known adenoma-adenocarcinoma sequence is available to guide their usage. EXPERIMENTAL DESIGN: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta Catenin

Share to MicroRNAs

Share to Oligonucleotide Array Sequence Analysis

Share to Rectum

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 21948089
DOI: 10.1158/1078-0432.CCR-11-1452
PMCID: PMC3544185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex patterns of altered MicroRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer.PMID 21948089Read ↗

Human miRNome Profiling in Colon Adenoma-carcinoma Sequence Reveal Early Deregulation of miR-1246, Which Exhibits Oncogenic Properties in Vitro by Targeting AXIN2 and CFTRSemantic proximity Read ↗

A dynamic miRNA-mRNA network serves as a crosstalk between abnormal cell cycle and immunosuppressive microenvironment in the colorectal adenoma-carcinoma sequenceSemantic proximity Read ↗

Differential expression of miRNAs between Young-Onset and Late-Onset Indian colorectal carcinoma patientsSemantic proximity Read ↗

MicroRNA in colorectal cancer: new perspectives for diagnosis, prognosis and treatment.Semantic proximity Read ↗

Colorectal adenoma and carcinoma specific miRNA profiles in biopsy and their expression in plasma specimensSemantic proximity Read ↗

Transcriptome-Wide Analysis and Experimental Validation from FFPE Tissue Identifies Stage-Specific Gene Expression Profiles Differentiating Adenoma, Carcinoma In-Situ and Adenocarcinoma in Colorectal Cancer ProgressionSemantic proximity Read ↗

Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression.Semantic proximity Read ↗

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerSemantic proximity Read ↗

Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative statesSemantic proximity Read ↗

Integrative Transcriptomic Analysis Reveals Tumor-Adjacent Mucosal Remodeling in Colorectal CancerSemantic proximity Read ↗

MicroRNA Expression Profile Reveals miR-17-92 and miR-143-145 Cluster in Synchronous Colorectal CancerSemantic proximity Read ↗

Serum MicroRNA profile in patients with colon adenomas or cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.