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Evidence of Epistatic Interactive Effects of HK1 and GCK Genes on Circulating Hemoglobin A1c Levels

2026-05-03

Abstract excerpt

<h4>Background</h4> Hemoglobin A1c (HbA1c), an important diagnostic biomarker for type 2 diabetes (T2D), is also associated with aging, cognitive performance, and mortality. To identify epistatic interactions, we assessed 133 known gene variants associated with HbA1c among 3,778 non-diabetic subjects of European ancestry in the Long Life Family Study (LLFS). <h4>Methods</h4> We applied Bayesian Imputation Based...

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Literature Corpus work
512758b5-da98-535d-bb54-be0283d10b8b
DOI
10.64898/2026.05.01.26352221
Open publication

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Evidence of Epistatic Interactive Effects of HK1 and GCK Genes on Circulating Hemoglobin A1c LevelsDOI 10.64898/2026.05.01.26352221
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